In this paper, we found that traditional descriptions of exploratory behavior (bold versus shy) do not fully capture individual differences in the behavior of adult zebrafish. Instead, we find that behavior falls into four categories: bold, shy, active explorers and wall-huggers.
This paper describes our adult zebrafish brain atlas (AZBA: azba.wayne.edu). This tool opens up new avenues in the use of adult zebrafish to understand vertebrate neuroanatomy.
Kenney, JW. "Associative and non-associative learning in adult zebrafish." Behavioral and Neural Genetics of Zebrafish. Academic Press, 2020. 187-204.
Guskjolen A, Kenney JW, de la Parra J, Yeung BA, Josselyn SA, Frankland PW (2018) Recovery of “lost” infant memories in mice. Current Biology, 28 (14), 2283-2290.
Xie J, Shen K, Lenchine RV, Gethings LA, Trim PJ, Snel MF, Zhou Y, Kenney JW, Kamei M, Kochetkova M, Wang X, Proud CG (2018) Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis. International Journal of Cancer, 142 (9), 1865-1877.
Wisse LE, Penning R, Zaal EA, van Berkel C, ter Braak TJ, Polder E, Kenney JW, Proud CG, Berkers CR, Altelaar MAF, Speijer D, van der Knaap MS, Abbink TEM (2017) Proteomic and metabolomic analyses of vanishing white matter mouse astrocytes reveal deregulation of ER functions. Frontiers in Cellular Neuroscience, 11, 411.
Kenney JW, Scott IC, Josselyn SA, Frankland PW (2017) Contextual fear conditioning in zebrafish. Learning and Memory, 24 (10), 516-523.
Vetere G*, Kenney JW*, Tran L, Xia F, Steadman PE, Parkinson J, Josselyn SA, Frankland PW (2017) Chemogenetic interrogation of a brain-wide fear memory network in mice. Neuron, 94 (2), 363-374.
Tanimizu T, Kenney JW, Kadoma K, Okano E, Frankland PW, Kida S (2017) Functional connectivity of multiple brain regions required for the consolidation of social recognition memory. The Journal of Neuroscience, 37 (15), 4103-4116.
Liu R, Kenney JW, Manousopoulou A, Johnston HE, Kamei M, Woelk CH, Xie J, Schwarzer M, Garbis SD, Proud CG (2016) Quantitative Non-Canonical Amino acid Tagging based proteomics identifies distinct patterns of protein synthesis rapidly induced by hypertrophic agents in cardiomyocytes, revealing new aspects of metabolic remodeling. Molecular & Cellular Proteomics, 15 (10), 3170-3189.
Leach PT, Kenney JW, Gould TJ (2016) c-Jun-N-terminal kinase 1 is necessary for nicotine-induced enhancement of contextual fear conditioning. Neuroscience Letters, 627, 61-64.
Kenney JW, Genheden M, Moon KM, Foster LJ, Proud CG (2016) eEF2K regulates the synthesis of microtubule-related proteins in neurons. Journal of Neurochemistry, 136 (2), 276-284.
Moore CEJ, Mikolajek H, Regufe da Mota S, Wang X, Kenney JW, Werner JM, Proud CG (2015) Elongation factor 2 kinase is regulated by proline hydroxylation and protects cells during hypoxia. Molecular and Cellular Biology, 35 (10), 1788-1804.
Leach PT, Kenney JW, Connor D, Gould TJ (2015) Thyroid Receptor-β Involvement in the Effects of Acute Nicotine on Hippocampus-Dependent Memory. Neuropharmacology, 93, 155–163.
Kenney JW, Sorokina O, Genheden M, Sorokin A, Armstrong JD, Proud CG (2015) Dynamics of eEF2K regulation in cortical neurons in response to synaptic activity. The Journal of Neuroscience, 35 (7), 3034-47.
Genheden M*, Kenney JW*, Johnston E, Manousopoulou A, Garbis SD, Proud CG (2015) BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1. The Journal of Neuroscience, 35 (3), 972–984.
Leach PT, Kenney JW, Gould TJ (2015) Stronger learning recruits additional cell signaling cascades: c-Jun-N-terminal kinase 1 (JNK1) is necessary for expression of stronger contextual fear conditioning. Neurobiology of Learning and Memory, 118, 162–166.
Panja D, Kenney JW, D’Andrea L, Zalfa F, Vedeler A, Wibrand K, Fukunaga R, Bagni C, Proud CG, Bramham CR (2014) Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK. Cell Reports, 9 (4), 1430–1445.
Kenney JW, Moore CE, Wang X, Proud CG (2014) Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles. Advances in Biological Regulation, 55, 15–27.
Gal-Ben-Ari S, Kenney JW, Ounalla-Saad H, Taha E, David O, Levitan D, Gildish I, Panja D, Pai B, Wibrand K, Simpson TI, Proud CG, Bramham CR, Armstrong JD, Rosenblum K (2012) Consolidation and translation regulation. Learning and Memory, 19 (9), 410–422.
Leach PT, Poplawski SG, Kenney JW, Hoffman B, Liebermann DA, Abel T, Gould TJ (2012) Gadd45b knockout mice exhibit selective deficits in hippocampus dependent long-term memory. Learning and Memory, 19 (8), 319–324.
Kenney JW, Poole RL, Adoff MD, Logue SF, Gould TJ (2012) Learning and nicotine interact to increase CREB phosphorylation at the jnk1 promoter in the hippocampus. PLoS One, 7 (6), e39939.
Gildish I, Manor D, Sharma V, Williams D, Agarawala U, Wang X, Kenney JW, Proud CG, Rosenblum K (2012) Impaired associative taste learning and abnormal brain activation in kinase-defective eEF2k mice. Learning and Memory, 19 (3), 116–125.
Gould TJ, Portugal GS, Andre JM, Tadman MP, Marks MJ, Kenney JW, Yildrim E, Adoff M (2012) The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation. Neuropharmacology, 62 (5), 2118–2125.
Kenney JW, Raybuck JD, Gould TJ (2012) Nicotinic receptors in the dorsal and ventral hippocampus differentially modulate contextual fear conditioning, Hippocampus, 22 (8), 1681–1690.
Portugal GS, Wilkinson DS, Kenney JW, Sullivan C, Gould TJ (2012) Straindependent effects of acute, chronic and withdrawal from chronic nicotine on fear conditioning. Behavioral Genetics, 42 (1), 133–150.
Kenney JW, Adoff MD, Wilkinson DS, Gould TJ (2011) The effects of acute, chronic and withdrawal from chronic nicotine on novel and spatial object recognition in male C57BL/6J mice. Psychopharmacology, 217 (3), 353–365.
Kenney JW, Wilkinson DS, Gould TJ (2010) The enhancement of contextual fear conditioning by ABT–418. Behavioural Pharmacology, 21 (3), 246–249.
Kenney JW, Florian C, Portugal GS, Abel T, Gould TJ (2010) Involvement of hippocampal jun–N terminal kinase pathway in the enhancement of learning and memory by nicotine. Neuropsychopharmacology, 35 (2), 483–492.
Marshall PJ, Kenney JW (2009) Biological perspectives on the effects of early psychosocial experience. Developmental Review, 29 (2), 96–119.
Kenney JW, Gould TJ (2008) Nicotine enhances context learning but not context shock associative learning. Behavioral Neuroscience, 122 (5), 1158–1165.
Kenney JW, Gould TJ (2008) Modulation of hippocampus–dependent learning and synaptic plasticity by nicotine. Molecular Neurobiology, 38 (1), 101–121.
Portugal GS, Kenney JW, Gould TJ (2008) β2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning. Neurobiology of Learning and Memory, 89 (2), 106–113.
Davis JA*, Kenney JW*, Gould TJ (2007) Hippocampal α4β2 nAChR involvement in the enhancing effect of acute nicotine on contextual fear conditioning. The Journal of Neuroscience, 27 (40), 10870–10877.